C20orf116
WebJun 13, 2014 · Amazon.com: C20orf116 antibody - middle region (ARP49787_P050) : Industrial & Scientific WebSep 19, 2024 · Except for the catalytic cysteine (C116) and a few other residues in its vicinity, UFC1 shares poor sequence homology with other E2 enzymes. However, it preserves the E2 fold of conjugating enzymes. Being an alpha/beta protein, UFC1 possesses four helices, three beta strands and a 3 10 -helix [ 31, 32 ].
C20orf116
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WebThe novel N-terminal domain shows a unique structure and plays a role in the recognition of its cellular substrate C20orf116 and thus in the recruitment of UfSP2 to the endoplasmic reticulum, where C20orf116 predominantly localizes. DDRGK1, also name as C20orf116, is a member of the DDRGK domain-containing protein family with unknown function. Depletion of DDRGK1 inhibits cell proliferation and invasion. Expression of NF-κB target genes showed the most significant decrease after depleting of DDRGK1, suggesting that DDRGK1 may play an important role in the NF-κB signaling ...
WebSep 2, 2010 · Biological assembly 1 assigned by authors and generated by PISA (software) Macromolecule Content Total Structure Weight: 109.35 kDa Atom Count: 6,716 Modelled Residue Count: 827 Deposited Residue Count: 962 Unique protein chains: 1 Display Files Download Files 3OQC Ubiquitin-fold modifier 1 Specific Protease, UfSP2 PDB DOI: … Webknown as C20orf116, DDRGK1, and Nashurin) as a novel Ufm1-binding protein and a potential Ufm1 target[8–11]. Using Ufbp1 as bait, they subsequently identified Ufl1 (Ufm1 ligase 1, also designated as KIAA0776, RCAD, NLBP, and Maxer) as a Ufbp1-interacting protein[8,11– 13]. When either overexpressed in HEK293 cells or in
Webfar only one protein C20orf116 has been identified as a target (Tatsumi et al., 2010). Neither is the functional significance of C20orf116 ufmylation known. Owing to the ability of C20orf116 to bind UFM1, it has been named UFM1-binding protein (UFBP1) (Lemaire et al., 2011). Therefore, C20orf116 henceforth was referred to as UFBP1. WebThe C20orf116 antibody - N-terminal region from MyBioSource.com is a Rabbit Polyclonal antibody. This antibody recognizes Human, Bovine, Canine, Horse, and Rabbit antigen. …
WebMar 25, 2011 · Recently, a Ufm1-specific E3 ligase, Ufl1, and its cellular substrate, C20orf116, have also been identified ( 3 ). Although the biological function of Ufm1 conjugation has yet to be identified, the fact that both Ufm1 and its conjugating system are conserved in both metazoans and plants suggests potential roles in various multicellular …
WebDDRGK domain containing 1. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. DDRGK1 (C20orf116, dJ1187M17.3, UFBP1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. Disease related genes. Human disease related genes. toct 10310WebFeb 19, 2010 · The C20orf116 x Ufm1 conjugate was cleaved by Ufm1-specific proteases, implying the reversibility of ufmylation. The conjugation was abundant in the liver and … penrhyn school hundletonWeb5116 SW 20th Ave, Cape Coral FL, is a Single Family home that contains 2318 sq ft and was built in 1988.It contains 3 bedrooms and 2 bathrooms.This home last sold for … penrhyn quarry zip world