WebChromatin assembly factor 1 (CAF1) is the only histone chaperone known to assemble histones H3 and H4 onto newly synthesized DNA both in vitro and in vivo [PMID:17065558]. The 938 amino acid multidomain p150 (CHAF1A) binds via its C-terminal third to p60, which is an essential step for nucleosome assembly because knocking down either subunit ... WebMar 5, 2024 · CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection. CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via …
CHAF1A - Wikipedia
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correlations between chaF1a expression and …
WebNov 25, 2024 · The assessment of CHAF1A as an independent predictor of poor outcome is also lacking. Moreover, the analysis is based on the expression of CHAF1A in gastric cancer at the mRNA level. It would be, perhaps, equally relevant to assess CHAF1A protein expression in a cohort of gastric cancer patients for which clinicopathological data is … WebJan 26, 2024 · Based on multi-step selection and validation, CHAF1B not only has a high diagnostic value in differentiating HCC patients from healthy controls but may also be a … WebMar 9, 2024 · Background: As distinct marker of proliferating cells, chromatin assembly factor-1 (CAF-1) was critical in DNA replication. However, there is paucity information about the clinical significance, functions and co-expressed gene network of CHAF1A, the major subunit in CAF-1, in cancer.Methods: Bioinformatic analysis of CHAF1A and its co … discount tire rockwall