Cholesteryl teg
WebThe addition of lipophilic groups to an oligonucleotide would be expected to enhance cellular uptake/membrane permeation. The use of cholesteryl oligos and the consequent improvement in activity has been described. We have designed our Cholesteryl products with triethyleneglycol (TEG) spacers for maximum solubility. WebCholesterol remains one of the most popular forms of labelling of oligonucleotides, especially those destined for use in therapeutics, including antisense and siRNA. 1,2 …
Cholesteryl teg
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WebCholesteryl-TEG-modified aptamers were embedded into the liposomal lipid bilayer while the interior cavity of the liposomes encapsulated fluorescent sulforhodamine B dye. WebThe addition of lipophilic groups to an oligonucleotide would be expected to enhance cellular uptake/membrane permeation. The use of Cholesterol-labelled oligos and the consequent improvement in activity has been described. We have designed our Cholesteryl …
WebCholesteryl-TEG. Cholesteryl-TEG is often used to increase the cell uptake of oligonucleotide. This modification has been shown to elicit cell uptake both in vitro and … WebDescription: 3'-Cholesteryl-TEG CPG. 1-Dimethoxytrityloxy-3-O- (N-cholesteryl-3-aminopropyl)-triethyleneglycol-. glyceryl-2-O-succinoyl-long chain alkylamino-CPG. F.W.: 755.97. Diluent: Not Applicable. Coupling: This support should be used in a manner identical to normal protected nucleoside support since it contains the DMT group.
WebCholesteryl-teg cep C70H106N3O11P - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine WebCholesteryl-TEG azide is an azide-containing cholesterol derivative that can be used as a reagent in the copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction to install a cholesteryl tag. It is also reported in the construction of novel anandamide-siRNA conjugates. [ 1] [ 2] 包装 100 mg in glass insert 其他说明
WebDec 1, 2009 · The cholesteryl-TEG-DNA presented in this work fulfills these criteria, andshowed that it stably inserts into the lipid coated LbL particles (Figure 32). [118] Membrane coated LbL particles ...
WebCholesteryl-conjugated oligonucleotides have been the subject of substantial interest in antisense and other studies due to the lipophilicity and good availability of cholesterol. One such study (1) has shown the use of cholesteryl … pine star trek actorWebCholesteryl chloroformate 95%; CAS Number: 7144-08-3; EC Number: 230-447-9; Synonyms: Chlorameisensäure-cholesterylester; find Sigma-Aldrich-C77007 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Cholesteryl-TEG azide. View Price and Availability. Sigma-Aldrich. C76604. … pine state garage wells meWebMar 5, 2024 · Cholesteryl-TEG-modified aptamers were embedded into the liposomal lipid bilayer while the interior cavity of the liposomes encapsulated fluorescent sulforhodamine B dye. Such liposomes ... top of my screen is blank