Chromomycin-a3
WebBiosynthesis of mithramycin, chromomycin A3, and their derivatives has been investigated in detail . In addition to their antiproliferative potency, AA antibiotics demonstrate an antiviral activity [9,10]. Mithramycin has been tested as a neuroprotector for Huntington’s disease and neuronal death [11,12]. WebDescription. Chromomycin A3, is used as a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye. Chromomycin A3 antagonizes enhanced …
Chromomycin-a3
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WebApr 6, 2024 · Chromomycin A3 (CMA3, Figure 17.1) is an antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseous. In the presence of bivalent … WebDec 1, 2014 · Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1-related anti-apoptotic proteins Paksiree Saranaruk, R. Kariya, +7 authors K. Vaeteewoottacharn Biology, Chemistry International journal of molecular medicine 2024 TLDR
WebChromomycin A 3 and mithramycin are antibiotics binding preferentially to the GC-rich regions of DNA. They have excitation maxima at 440 nm and emission maxima at 555 … WebChromomycin A3. 230752-10MG. 80055-168EA 310.68 USD. 80055-168. Chromomycin A3. Chromomycin A3. Antibiotic that inhibits RNA synthesis. Excitation maximum: …
WebChromomycin A3 Revision Date 20-Feb-2024 www.alfa.com Revision Date 20-Feb-2024 Print Date 20-Feb-2024 Revision Summary SDS authoring systems update, replaces ChemGes SDS No. 7059-24-7. Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the WebDriving Directions to Tulsa, OK including road conditions, live traffic updates, and reviews of local businesses along the way.
WebDec 4, 2014 · The present study highlights the biological effects of chromomycin A2 toward metastatic melanoma cells in culture. Besides chromomycin A2, chromomycin A3 and demethylchromomycin A2 were also identified from the extract derived from Streptomyces sp., recovered from Paracuru Beach, located in the northeast region of Brazil. The …
WebApr 27, 2024 · Chromomycin A3 (which is interesting also an antibiotic!), which binds to GC-rich regions of DNA. A Hoechst stain (e.g. 33258 or 33342), that binds to AT-rich regions. Using these DNA stains, we can separate the larger chromosomes from the smaller ones as they will contain more DNA and will thus yield a greater fluorescence signal. how is surface water naturally purifiedWebChromomycin A 3 is an anthraquinone antibiotic and antitumor agent isolated from S. griseus that is used as a fluorescent probe for DNA with excitation/emission spectra of 445/575 nm. 1, 2 Its DNA binding is specific to two or more contiguous GC base pairs, which makes it suitable for characterizing heterochromatin in plants with species ... how is surface coal minedWebApplication: Chromomycin A3 is a G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye CAS Number: 7059-24-7 Purity: ≥97% Molecular Weight: 1183.25 Molecular Formula: C 57 H 82 … how is surface area calculatedWebDec 4, 2014 · Chromomycin A3 / metabolism Chromomycins / pharmacology HCT116 Cells HL-60 Cells Humans Melanoma / drug therapy* Melanoma / metabolism … how is survivor filmedChromomycin A3 (CMA3) or Toyomycin is an anthraquinone antibiotic glycoside produced by the fermentation of a certain strain of Streptomyces griseus (No. 7). See more In the presence of Mg ions, Chromomycin A3 binds reversibly to DNA, preferentially to contiguous G/C base pairs. When bound to DNA, Chromomycin A3 has a maximum excitation wavelength of 445 See more • in-vitro membrane-impermeant G/C-specific fluorescent DNA-binding dye. • in-vitro antibiotic of gram-positive bacteria, through inhibition of the incorporation of Pi in the RNA. • in-vitro anticancer drug that inhibits RNA synthesis. See more how is susan boyle doing these daysWebChromomycin A3 has a variety of utilities as a staining agent for human sperm chromatin, autophagy inducing agent, and apoptosis inhibitor. For research use only. We do not sell to patients. Chromomycin A3 … how is susan la flesche recognized todayhow is susan boyle doing