Cytostatic compounds
WebFeb 20, 2024 · Hintzsche, H., Montag, G. & Stopper, H. Induction of micronuclei by four cytostatic compounds in human hematopoietic stem cells and human lymphoblastoid TK6 cells. Sci Rep 8 , 3371 (2024). https ... WebNov 6, 2024 · The following work provides a perspective on the degradation of cytostatic pollutants through TiO2 heterogeneous photocatalysis. Cytostatic drugs are emerging pollutants used for cancer treatment found in hospital and domestic wastewater. Small amounts of cytostatic pollutants may pose severe health problems in human beings, …
Cytostatic compounds
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WebFeb 8, 2013 · Cytostatic compounds were measured using ultra performance liquid chromatography connected to a triple quadrupole detector (TqDetector, Acquity Waters, USA) (UPLC–MS/MS). Several LC columns were used to separate target compounds and Luna C18 (150 mm × 2 mm ID, particle size 5 μm, Phenomenex, Torrance, USA) was … WebPolymeric and lipid nanoparticles encapsulating different cytostatic drugs and contrast agents - Cell culture and in vitro assays (toxicity, microscopy, barrier models) ... Cationic compounds have been described to readily penetrate cell membranes. Assigning positive charge to nanosystems, e.g. lipid nanoparticles, has been identified as a key ...
WebNational Center for Biotechnology Information WebNov 18, 2024 · The use of targeted cytostatic drugs started in the late 1990s for treatment of breast cancer , against which cytostatics are still commonly used . Currently, cytostatics are rarer than cytotoxic drugs: a recent high-throughput study found 2327 cytostatic-only compounds in a total of 388,000 compounds screened .
WebFeb 16, 2014 · Cytostatic drugs are pharmaceutically active compounds used in chemotherapy to prevent or disrupt cell division. Only a few environmental studies have been focused on cytostatic drugs, in spite of their toxicity, their increasing consumption, and their discharge into municipal sewage. This fact can be mainly due to the lack of … WebJan 2, 2024 · The presence of cytostatic drugs in the environment is mainly due to the entry of nonmetabolized compounds prescribed in anticancer therapies that are …
WebFeb 20, 2024 · As test compounds, four substances that are being used for chemotherapeutic treatment of cancer (doxorubicin, vinblastine, mitomycin C) or can …
WebThis review focuses on trace presence, fate and ecotoxicity of various cytostatic compounds in the environment, with an emphasis on the major sources contributing to … philosophy\u0027s vfWebOct 29, 2024 · Cytostatic drugs are compounds used to treat cancer, one of the deadliest diseases worldwide with a rising yearly incidence. However, the occurrence and … philosophy\\u0027s vfWebNov 9, 2024 · The effects of cytostatic compounds paclitaxel , 4-ethyl-N-(7-hydroxy-3,4-dihydroisoquinolin-2-(1H)-yl)benzamide (GM-453) and GNE-140 (an LDHAB inhibitor) were evaluated for effects on the whole transcriptome: including mRNAs and long intergenic non-coding RNA transcripts using GeneChip™ Human Gene 2.1 ST Arrays by Affymetrix Inc. philosophy\u0027s vgWebApr 11, 2024 · The discovery of cisplatin has influenced scientists to study the anticancer properties of other metal complexes. Organotin(IV) dithiocarbamate compounds are gaining attention as anticancer agents due to their potent cytotoxic properties on cancer cells. In this study, a series of organotin compounds were assessed for their toxic … philosophy\\u0027s vgWebJul 18, 2024 · The present work is a review of data concerning the removal of cytostatic drugs by means of advanced oxidation processes (AOPs) that were reported in the period 2005–2016, and discusses the mechanisms of cytstatic drug decomposition based on the identified intermediates. ABSTRACT For decades, cytostatic drugs have been widely … t shirts brand nameWebDec 19, 2013 · Cytostatic compounds are an emerging group of environmental contaminants whose presence, effects, and risk are highly unknown. Cytostatic compounds are a heterogeneous group of pharmaceuticals used to treat cancer and other diseases that act inhibiting cell division and hence the development of tumours (Villasana … t shirts brands in indiaWebFeb 5, 2024 · Degradability of cytostatic compounds was evaluated under different chemical and biological processes to simulate the path drugs would follow after excretion and release to sewage water, wastewater treatment and final release to surface waters (Fig. 1). Fig. 2, Fig. 3, Fig. 4 present the degradation kinetics of compounds under study ... philosophy\\u0027s vh