WebFig. 3 Global architecture of the Fpg extrahelical base binding pocket. As indicated, the cFapydG (green)-containing DNA (gray) is stabilized in extrahelical conformation in a large Fpg cavity. The accessibility surfaces of the protein clearly show that this cavity is highly exposed to water molecules. WebFeb 22, 2007 · Biological assembly 1 assigned by authors. Macromolecule Content Total Structure Weight: 31.21 kDa Atom Count: 2,582 Modelled Residue Count: 242 Deposited Residue Count: 242 Unique protein chains: 1 Unique nucleic acid chains: 2 Display Files Download Files 2OYT Crystal Structure of UNG2/DNA (TM) PDB DOI: …
RCSB PDB - 2OYT: Crystal Structure of UNG2/DNA(TM)
WebFeb 18, 2011 · The extrahelical bases resulting from folding of attC bottom strands are important for the recognition by integrases. These enzymes are directly involved in the accumulation and formation of new cassette arrangements in the variable region of integrons. Thus, it is important to better understand interactions between IntIs and their … WebMar 25, 2008 · The free energies projected onto d 1 and d 2 (the unstacking step) were essentially the same for the two bases, with the extrahelical conformation somewhat lower in free energy than the intrahelical conformation. That the protein significantly stabilizes a base separated state (compare with SI Fig. 8) ... fact meaning in kannada
Enzymatic capture of an extrahelical thymine in the search for …
WebFeb 18, 2011 · Integron integrases (IntIs) bind specifically to the bottom strand of attC sites. The extrahelical bases resulting from folding of attC bottom strands are important … WebJan 5, 2024 · extrahelical (not comparable) Beyond, or temporarily removed from the double helix, of a nucleic acid molecule; Usage notes . Used especially to describe … WebE-motif formed by extrahelical cytosine bases in DNA homoduplexes of trinucleotide and hexanucleotide repeats. Nucleic Acids Research 2024, 46 (2) , 942-955. DOI: … fact maps