WebR.J. Preston, J.A. Ross, in Comprehensive Toxicology, 2010 1.16.3.5 Halogenated Hydrocarbons. Occupational exposure to vinyl chloride is associated with a high … WebVinyl chloride is thought to depress the CNS via a solvent effect on lipids and protein components of neural membranes that interrupts signal transmission. Reactive metabolic intermediates may also cause specific target organ toxicity by covalently bonding to tissue or initiating destructive chain reactions such as lipid peroxidation.
Metabolism of 14 C-vinyl chloride in vitro and in vivo - PubMed
Web1 okt. 1976 · Vinyl chloride (VCM) is not carcinogenic by itself, it is bioactivated to the highly reactive alkylating oxirane chloroethylene oxide. Further metabolism, apparently, … Web9 feb. 2024 · It is well known that the risk for developing chronic liver injury is influenced by multiple factors, such as genetics, comorbidities, and/or lifestyle choices, such as diet. … exclusive usernames
Vinyl chloride dysregulates metabolic homeostasis and …
WebVinyl Chloride H2C=CHCl or C2H3Cl CID 6338 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … Webmetabolism of vinyl chloride in mammals and in man, including the formation of monochloroacetic acid and some identified sulfur conjugates is reviewed. Hepatic micro … Web8 mrt. 2016 · Vinyl chloride (VC) is an organochlorine used to create the polymer, polyvinyl chloride. VC is ranked as the 4th most important toxic chemical on the Hazardous … exclusive travel partners reviews