WebPhorbol 12-myristate 13-acetate (PMA), a phorbol ester, is a reversible, highly potent activator of protein kinase C (PKC), including Group A and Group B isoforms (Blumberg). PMA activates PKC isoforms through the binding of the C1 domain (Hurley et al.). WebPhorbol 12-myristate 13-acetate (PMA), also known as 12-O-tetradecanoylphorbol 13-acetate (TPA), is a specific activator of Protein Kinase C (PKC) and hence activates …

CAS 638-59-5 Myristyl acetate - BOC Sciences

WebPhorbol 12-myristate 13-acetate (PMA), PKC activator (DMSO solution) Description PKC activator (DMSO solution) Alternative names PMA Biological description Potent nanomolar activator of protein kinase C in vivo and in vitro. Binds to C1 domain of protein kinase C, induces membrane translocation and enzyme activation. WebDec 1, 2003 · Before assaying for hB - FVIII activity, the platelets were thawed and phorbol myristyl acetate (final concentration, 1 μM) and collagen (final concentration, 5 mg/mL) were added. After spinning down the platelet membranes at 600 g for 15 minutes, hB - FVIII level was determined in the platelet releasate. curle_failed_init

Phorbol - Wikipedia

WebPhorbol-12-myristate-13-acetate, CAS 16561-29-8, acts as an extremely potent mouse skin tumor promoter. Activates protein kinase C in vivo and in vitro at nM concentrations. MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS CoA References Brochures Data Sheet Citations WebWe found that the invariant natural killer T cells in the lungs of patients with asthma produced both interleukin-4 and interleukin-13 but little interferon-γ on intracellular cytokine staining... WebMay 1, 2001 · In some experiments, U937 cells were incubated with pure flavonoid or plasma extract in a 25-mL culture flask (Becton Dickinson Labware) for 20 h, activated with phorbol myristyl acetate (PMA; 100 μg/L) for 2 h, and then fluorescently labeled. curl elasticsearch auth