WebFeb 3, 2024 · RNA binding proteins play an important role in regulating alternative pre-mRNA splicing and in turn cellular gene expression. Polypyrimidine tract binding proteins, … WebApr 6, 2024 · Polypyrimidine tract-binding protein function is controlled by a set of co-recruited proteins and importantly provide further evidence that it is possible to dictate …
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WebAug 23, 2024 · Metabolic and proliferative state of vascular adventitial fibroblasts in pulmonary hypertension is regulated through a MicroRNA-124/PTBP1 (polypyrimidine tract binding protein 1)/pyruvate kinase muscle axis. Circulation. 2024; 136:2468–2485. doi: 10.1161/CIRCULATIONAHA.117.028069 Link Google Scholar; 8. WebPolypyrimidine tract-binding protein homolog 1. Gene. PTB. Status. UniProtKB reviewed (Swiss-Prot) Organism. Arabidopsis thaliana (Mouse-ear cress) Amino acids. 399. ... Binds to the polypyrimidine tract of introns. May promote the binding of U2 snRNP to pre-mRNA (By similarity). By similarity. tari pangngadakkang
Splice factor polypyrimidine tract-binding protein 1 (Ptbp1) primes ...
WebDec 27, 2024 · Polypyrimidine tract–binding protein 1 (PTBP1), an essential gene for the Warburg effect, regulates this cancer‐specific energy metabolism via alternative splicing (AS) of pyruvate kinase. 6 PTBP1 decreases the expression of the M1 isoform of pyruvate kinase (PKM1) and promotes the expression of PKM2, which leads mainly to a metabolic … WebFeb 22, 2004 · Tillmar, L. & Welsh, N. Hypoxia may increase rat insulin mRNA levels by promoting binding of the polypyrimidine tract-binding protein (PTB) to the pyrimidine-rich … WebAug 17, 2015 · The polypyrimidine tract-binding (PTB) family of proteins represent a multifaceted group of proteins that binds numerous mRNAs and have been implicated in … tari panarat