WebJan 3, 2014 · An efficient, library amenable, "pot economical" total synthesis of (+)-strictifolione and the related natural product, (6R)-6[(E,4R,6R)-4,6-dihydroxy-10-phenyl-1-decenyl]-5,6-dihydro-2H-2-pyrone, are reported. This modular approach takes advantage of two consecutive phosphate tether-mediated, one-pot, sequential protocols, followed by a … WebDec 2, 2013 · Recently, the potential of phosphate tethered facilitated processes were highlighted in the pot-economical and efficient total synthesis of the antifungal agent strictifolione, whereby two...

Total Synthesis of (+)‐Strictifolione., ChemInform DeepDyve

WebDec 2, 2013 · An efficient, library amenable, “pot economical” total synthesis of (+)-strictifolione and the related natural product, (6R)-6[(E,4R,6R)-4,6-dihydroxy-10-phenyl-1-decenyl]-5,6-dihydro-2H-2-pyrone are reported.This modular approach takes advantage of two consecutive phosphate tether-mediated, one-pot, sequential protocols, followed by a … WebFeb 18, 2003 · Abstract Starting from (S)-malic acid and (S)-glycidol, the first total synthesis of strictifolione, a new 6- (ω-phenylalkenyl)-5,6-dihydro-α-pyrone isolated from Cryptocarya strictifolia, was... en an ice cube shrinks

Stereoselective total synthesis of (+)-strictifolione and (6 R)-6-[(4 R …

WebNov 4, 2010 · A concise and practical enantioselective synthesis of (+)‐strictifolione has been achieved in high diastereomeric excess using Jacobsen's hydrolytic kinetic resolution, proline‐catalyzed sequential α‐aminoxylation and Horner–Wadsworth–Emmons olefination of aldehyde and cross olefin/ring‐closing metathesis as the key steps. Citing Literature A concise and practical enantioselective synthesis of (+)-strictifolione has been achieved in high diastereomeric excess using Jacobsen's hydrolytic kinetic resolution, proline-catalyzed sequential α-aminoxylation and Horner–Wadsworth–Emmons olefination of aldehyde and cross olefin/ring-closing metathesis as the key steps. WebWe describe a concise and straightforward approach to the total syntheses of (+)-Strictifolione and Cryptofolione in the longest linear sequences of four steps and six … dr bowie weatherford ok